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The Causes of Adult Diabetic Nephropathy
The cause of adult Diabetic Nephropathy is not well understood, but it is thought that high blood sugar, advanced glycation end product formation, and cytokines may be involved in the development of diabetic nephropathy.
Kidney damage is likely if one or more of the following is present:
Poor control of blood glucose
High blood pressure
Type 1 diabetes mellitus (before age 20)
History of cigarette smoking
A family history of kidney problems